Neuron Specific Enolase (NSE)

Cat. No. : 0416
Name: Neuron Specific Enolase(NSE)Mouse monoclonal Antibody
Type: Mouse monoclonal
Immunogen: A synthetic peptide corresponding to aa416-433 of human NSE gamma
Species Reactivity:  human, others not-known.
Clone: ENO2/1375
Isotype: IgG2b
Cellular Localization: Cytoplasmic
Concentrated antibody Dilution: 1:50-1:100
Antigen retrieval: Citrate
Intended Use: IVD 
Storage: Store at 2-8°C. Do not freeze.

Recognizes a protein of 46kDa, identified as neuron-specific enolase (NSE). Enolases are homo-or heterodimers of the three subunits: alpha (46kDa), beta (44kDa), and gamma (46kDa). This antibody shows no cross-reaction with the alpha- or beta-subunits of NSE. The alpha-subunit is expressed in most tissues and the beta-subunit only in muscle. The gamma-subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms. This antibody is superb for immunohistochemical staining of formalin-fixed, paraffin-embedded tissues.

Cat. No. Size
R-0416-06 Ready to Use: 6mL
M-0416-1.0 Concentrated: 1mL
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