The anti-Cytokeratin (CAM 5.2) reagent is a murine monoclonal antibody used for qualitative identification of normal cells and malignant cells of epithelial origin in tissue sections (paraffin and frozen) and cytocentrifuge preparations. The clinical interpretation of any staining or its absence should be complemented by morphological studies and proper controls (such as positive, negative, and isotype-matched controls). All tests should be performed by a qualified individual.
Anti-Cytokeratin (CAM 5.2) reagent stains most epithelial-derived tissue, including liver, renal tubular epithelium, and hepatocellular and renal cell carcinomas. Anti-Cytokeratin (CAM 5.2) reagent does not stain stratified squamous epithelium and may not react with some cases of squamous cell carcinoma. Expected results may vary with tissue.