Bcl-2

Cat. No. : 0025
Name:Bcl-2 Recombinant Mouse Monoclonal Antibody 
Type: Recombinant Mouse Monoclonal
Immunogen: A synthetic peptide, aa 41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein
Species Reactivity:  human, others not-known.
Clone: rMM-B1
Isotype:  IgG2a kappa
Cellular Localization: Cell membrane and Cytoplasmic
Concentrated antibody Dilution: 1:50-1:100
Antigen retrieval: EDTA
Intended Use: IVD 
Storage: Store at 2-8°C. Do not freeze.

Recognizes a protein of 25-26kDa, identified as the Bcl-2 oncoprotein. This antibody shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 protein, whereas the normal or hyperplastic germinal centers are negative.

Cat. No. Size
R-0025-06 Ready to Use: 6mL
M-0025-1.0 Concentrated: 1mL
;