Catalogue Number: FS-286
Intended Use: RUO
Chromosome: CSP 13
Aliases: RB, pRb, OSRC, pp110, p105-Rb, PPP1R130
Standard Design: Red ( RB1 ) / Green ( CSP13 )
Color: You may also choose the color of the dye to customize the probe to meet your needs.
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
| Code | Test Kits | |
| FS-286-05 | 5 tests | 50 μL |
| FS-286-10 | 10 tests | 100 μL |
| FS-286-20 | 20 tests | 200 μL |