Cat. No. : 0373
Name: MART-1/Melan-A Recombinant Mouse Monoclonal Antibody
Type: Recombinant Mouse Monoclonal
Immunogen: Recombinant MART-1 protein
Species Reactivity: human, others not-known.
Clone: rMM-M1
Isotype: IgG1, kappa
Cellular Localization: Cytoplasmic
Concentrated antibody Dilution: 1:40-1:80
Antigen retrieval: Citrate
Intended Use: IVD
Storage: Store at 2-8°C. Do not freeze.
Recognizes a protein of ~20kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. This antibody does not cross-react with MAGE-1 or tyrosinase protein. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. MART-1/Melan-A antibody label melanomas and other tumors showing melanocytic differentiation. They do not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
| Cat. No. | Size |
| R-0373-06 | Ready to Use: 6mL |
| M-0373-1.0 | Concentrated: 1mL |