Cat. No. : 0399
Name: Mucin 5AC (MUC5AC) Mouse monoclonal Antibody
Type: Mouse monoclonal
Immunogen: M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b-) patient
Species Reactivity: human, others not-known.
Clone: ZM148
Isotype: IgG1 kappa
Cellular Localization: Cytoplasmic
Concentrated antibody Dilution: 1:50-1:100
Antigen retrieval: Citrate
Intended Use: IVD
Storage: Store at 2-8°C. Do not freeze.
Recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
| Cat. No. | Size |
| R-0399-06 | Ready to Use: 6mL |
| M-0399-1.0 | Concentrated: 1mL |