Cat. No. : 0432
Name: P170/p-Glycoprotein/MDR Rabbit monoclonal Antibody
Type: Rabbit monoclonal
Immunogen: A synthetic peptide corresponding to residues of human MDR-1 protein
Species Reactivity: Human, others not-known.
Clone: EP271
Isotype: Rabbit IgG
Cellular Localization: Cell membrane
Concentrated antibody Dilution: 1:20-1:80
Antigen retrieval: EDTA
Intended Use: IVD
Storage: Store at 2-8°C. Do not freeze.
The resistance of tumour cells to cytotoxic chemotherapeutic drugs is a major problem in the treatment of cancer. Recent studies have linked the presence of a 170 to 180 KD cell membrane protein, P-glycoprotein, with resistance to a wide range of lipophilic chemotherapeutic drugs, a phenomenon known as multidrug resistance. P-glycoprotein is found in transporting epithelia of several normal tissues, including liver, kidney, colon, adrenal and brain.
| Cat. No. | Size |
| R-0432-06 | Ready to Use: 6mL |
| M-0432-1.0 | Concentrated: 1mL |