Cat. No. : 0238
Name: EGFR Recombinant Rabbit Monoclonal Antibody
Type: Recombinant Rabbit Monoclonal
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGFR
Species Reactivity: Human, others not-known.
Clone: rRM-E1
Isotype: Rabbit IgG
Cellular Localization: Cell membrane
Concentrated antibody Dilution: 1:25-1:50
Antigen retrieval: EDTA
Intended Use: IVD
Storage: Store at 2-8°C. Do not freeze.
It recognizes a 170kDa protein, identified as the first member (EGF-Receptor) of type I family of growth factor receptors. Its epitope maps in the EXTRACELLULAR domain of EGFR. It shows no cross-reaction with c-erbB-2, c-erbB-3, or c-erbB-4. It blocks the binding of EGF to EGFR. Overexpression of EGFR is reported in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. EGFR is predominantly overexpressed in squamous cell carcinomas. This antibody is superb for staining of routine formalin/paraffin tissues.
| Cat. No. | Size |
| R-0238-06 | Ready to Use: 6mL |
| M-0238-1.0 | Concentrated: 1mL |